At the most basic level, this is how it works: In younger people, the genes that control the health of muscle cells and regulate the muscle’s use of energy express themselves at optimal levels. As we age, some of these genes get turned up (up-regulated) and some of these genes get turned down (down-regulated). The genes that are up-regulated, or become more expressed with age, are those involved with cell repair, DNA repair, and cell death. The genes that tend to get down-regulated, or become less expressed with age, are those associated with a part of our cells called the mitochondria, which is responsible for efficiently turning nutrients into energy.

Based on these changing levels of genetic expression, it is not surprising to find that skeletal muscle in older people exhibits more cell death and mitochondrial dysfunction as compared to younger people. Without exercise, this leads to muscle weakness and impairment, and eventually muscle atrophy, known as sarcopenia.

Melov and his colleagues designed their study to determine whether muscle decline was reversible all the way down to the genetic level. To this end, skeletal muscle of a group of younger, healthy adults and a group of healthy, active, disease-free, older adults was acquired from all subjects. The muscle in both groups underwent genetic expression profiling before the older group embarked upon a resistance exercise program, and then again at the conclusion of the program.

The study identified 596 genes in the skeletal muscles that were expressed differently in older and younger individuals. Of these 596 age related genes, 179 were impacted by the resistance exercise performed by the older group.

At the end of the study, the findings were striking: As a result of the six-month resistance exercise program, the genetic profile of the skeletal muscles in the older individuals substantially resembled the genetic profile observed in the younger group. The expression of the 179 age-related genes impacted by the exercise had returned to younger levels!

The leg muscles of the older subjects were also 50 percent stronger than before training, but more significantly –– and because of the genetic changes –– the usual age-induced impairments in cell repair activities and mitochondrial function were reduced. The implications of this study are potentially enormous, since it is estimated that only about 12 percent of the population over age 65 engages in resistance exercise twice a week.

Hall Longevity Clinic, was cofounded by Dr. Cary and myself.  We started a general medicine clinic in South Beach serving the great and diverse Miami area.  We are both diplomats and current members of the American Board of Family Practice and have twenty years combined experience practicing medicine throughout the world, from Sri Lanka to Maui, from Maine to New Zealand, New Orleans , to New York City.

Hall Longevity Clinic is designed as a “hybrid clinic,” serving preventative, general medical and aesthetic needs.  We offer a variety of basic medical services, including full physical exams and blood screenings, as well as comprehensive STD testing, travel medicine and vaccines, (CDC endorsed), metabolic weight loss programs and the popular ALCAT food sensitivity blood test.  We are the only practice in Miami Beach licensed to provide Spectracell and Lipoprotein testing.  On the aesthetic side, we work without scalpels and exclusively with the Cutera XEO laser—the premier system for anti-aging, facial rejuvenations treatments and safe laser hair reduction.   Moreover, we are also proud to offer advanced techniques with Botox, Myobloc and the facial filler Restylane.

Our goal is to provide a safe, tranquil and welcoming environment, where patients can feel at home while receiving the very best care possible.  Located on Lincoln Road, Hall Longevity Clinic eliminates wait times and our physicians spend at least an hour with new patients, almost four times the national average.  We also provide all of our services through our very discreet and personalized “house calls” at the Setai Hotel.

Thank you for the opportunity to participate in caring for your client’s health care.  Please feel free to contact us anytime for questions or concerns at 305 672 4733

Hosting celebrities, supermodels and fashion insiders, Mercedes-Benz Fashion Week “Swim” is the hottest event of the Summer in the sexiest city in the world: Miami Beach.  Held annually at the iconic Raleigh hotel (where Karl Lagerfeld recently unveiled the Chanel Cruise Collection 2008), the event showcases the world’s most exciting swimwear designs during a week of unprecedented sensuality and glamour.  Hall Medication Foundation has been named an official sponsor by IMG Fashion and will be providing exclusive product and service demonstrations for VIP guests.   Transforming Raleigh penthouse, a mobile Hall Longevity Clinic will showcase the cutting edge medical testing and technology available through Hall Medical Foundation.

Drs. Michael and Cary Hall will be demonstrating skin rejuvenation and wellness with their Cutera and Fraxel lasers, Restylane fillers and exclusive food allergy blood tests with ALCAT laboratories, as well discussing the benefits of human growth hormone and secret medical weight loss strategies. We perceive this synergy between medicine and fashion as proof that with true vision, not only can one see well into the future, one can actually change it.  We have dedicated this sponsorship to the very people who make the term visionaries.  From our own forward thinking founders, Drs. “Michael” and “Cary”, we know that the world is becoming a smaller and a more intertwined place; an environment dictated by form over function and where slight-of-hand carries more weight than actual substance.

As health care experts, we are acutely aware of the needs of society and our patients; creating a new paradigm, we are fully committed to serve purposely and compassionately!I t is our mission to deliver a “health experience” and create a formative dialogue between medicine, technology and our patient’s needs. Indeed, we are different and are proud to say that it is so. We are owned and operated by a family of physicians driven toward performance and developing the very best health care system in the world.

Mercedez Benz and Hall Longevity

To emphasize our dedication to aesthetics and wellness, we now have the unique opportunity to be the world’s first medical presence at a truly global event. You’ll be happy to know you have a front row seat to what will be tomorrow.  See you at Mercedes Benz Swim!